Thymosin Alpha-1 Dosage: Doses Studied, Units and Chart
What doses of Thymosin Alpha-1 have been used in published research, how they convert to syringe units, and what is still unknown.
- Doses studied
- 6 studies
- with a stated dose, listed below
- Frequency
- Varies by study
- as used in studies
- Half-life
- elimination half-life less than 3 hours; Tmax 1-2 hours
- subcutaneous, in people · International journal of clinical pharmacology and therapeutics 1999, PMID 10027483
Doses used in published studies
Each dose below is quoted from a study abstract, strongest design first. Animal doses are labelled and do not translate directly to people. None of them is a recommendation.
| Dose | Frequency and route | Study type | Source |
|---|---|---|---|
| not stated in abstract | every 12 hours · subcutaneous · seven days | Human RCTn = 1106 | BMJ 2025, PMID 39814420 |
| 3.2 mg | twice per day · injection · 7 days | Human RCTn = 24 | Inflammation 2011, PMID 20549321 |
| 1.6 mg | 5 times weekly · SC · 24 weeks | Human RCTn = 25 | Hepatology international 2009, PMID 19669251 |
| 0.8 mg or 1.6 mg | six times weekly for two weeks, then twice weekly · not stated · 24 weeks | Human RCTn = 16 | Internal medicine 2003, PMID 14606705 |
| 900 microg/m2 | single dose and 5-day multiple dose · subcutaneous | Human RCTn = 9 | International journal of clinical pharmacology and therapeutics 1999, PMID 10027483 |
| 1.6 mg | qd or q12 h · not stated · more than 5 days | Human observationaln = 334 | International immunopharmacology 2020, PMID 32795897 |
Before anyone considers it
- Thymosin Alpha-1 is Not FDA approved · approved abroad; research-chemical versions are not the approved drug.
- Compounded and research-chemical versions are not the approved product and are not checked by the FDA for identity, purity or dose.
- Reconstitution math (mg vs mcg, units vs mL) is the most asked question in peptide forums. Check every number twice.
- People who are pregnant, breastfeeding, or have a chronic condition need medical advice first.
Common questions
Is Thymosin Alpha-1 FDA approved?
Thymosin Alpha-1 is Not FDA approved · approved abroad. Products sold as research chemicals are not the approved drug and are not checked by the FDA.
More on Thymosin Alpha-1
Sources
- 1Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
- 2BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
- 3The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial.BMJ (Clinical research ed.) · 2025PMID 39814420Accessed 2 Oct 2026
- 4Thymosin alpha 1 is associated with improved cellular immunity and reduced infection rate in severe acute pancreatitis patients in a double-blind randomized control study.Inflammation · 2011PMID 20549321Accessed 2 Oct 2026
- 5A randomized controlled trial of thymalfasin plus transarterial chemoembolization for unresectable hepatocellular carcinoma.Hepatology international · 2009PMID 19669251Accessed 2 Oct 2026
- 6A pilot study of thymosin alpha1 therapy for chronic hepatitis B patients.Internal medicine (Tokyo, Japan) · 2003PMID 14606705Accessed 2 Oct 2026
- 7Pharmacokinetics of thymosin alpha1 after subcutaneous injection of three different formulations in healthy volunteers.International journal of clinical pharmacology and therapeutics · 1999PMID 10027483Accessed 2 Oct 2026
- 8Thymosin α1 therapy in critically ill patients with COVID-19: A multicenter retrospective cohort study.International immunopharmacology · 2020PMID 32795897Accessed 2 Oct 2026
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