hCG Reconstitution Calculator (IU to Units)
- Concentration
- 1000 IU/mL
- Doses per vial
- 10
- Weeks (1 dose/wk)
- 10
100 units (1 mL) on a 1 mL U-100 syringe: 1000 IU from a 10000 IU vial + 10 mL water (hCG).
Dosing table for a 10000 IU vial
Syringe units (U-100) for each dose, by how much bacteriostatic water you add.
| Dose | 1 mL water | 5 mL water | 10 mL water |
|---|---|---|---|
| 500 IU | 5 | 25 | 50 |
| 1000 IU | 10 | 50 | 100 |
| 2000 IU | 20 | 100 | 200 |
| 4000 IU | 40 | 200 | 400 |
| 5000 IU | 50 | 250 | 500 |
| 10000 IU | 100 | 500 | 1000 |
How the math works
Concentration is the vial's IU divided by the water you add. Volume to draw is your dose divided by that concentration. On a U-100 syringe, 1 mL is 100 units, so units = mL × 100.
1000 IU ÷ 1000 IU/mL = 1 mL
1 mL × 100 = 100 units
What is the difference between IU and units on the syringe?
IU measures hormone potency in the vial; a U-100 syringe unit is one hundredth of a millilitre. At 1,000 IU/mL, each syringe unit holds 10 IU.
Calculated from concentration IU per mL 1000; u100 units per mL 100. Formula: IU per syringe unit = (IU/mL) / 100 = 10
How long does reconstituted hCG last?
Per the Novarel label, reconstituted product is refrigerated and used within 30 days.[3]
Vial sizes, water volumes and preset doses are amounts quoted in hCG labels, used here for the arithmetic only. They are not dosing guidance. The amount is in IU throughout: nothing is converted to mg.
The vial strengths on the chorionic gonadotropin labels
Novarel is supplied as multiple-dose vials of 5,000 or 10,000 USP units.[3]
The Pregnyl label lists a single 10,000 USP unit multiple-dose vial.[4]
The labels count potency in USP units, which this calculator treats as the same IU figure printed on the vial.[3]
Diluent and volume as the labels describe them
Each Novarel vial comes with a 10 mL vial of bacteriostatic water containing 0.9% benzyl alcohol.[3]
The Pregnyl directions say to remove 1 to 10 mL of solvent and add it to the powder.[4]
Novarel's label says to refrigerate the reconstituted product and use it within 30 days.[3]
The Pregnyl label sets its own, longer limit for the refrigerated reconstituted solution.[4]
Worked example on a label strength
Arithmetic on label figures: a 5,000 or 10,000 IU vial mixed with 1, 2, 5 or 10 mL gives these concentrations, and the label's 500 USP unit injection volume would read as follows: 5,000 IU in 1 mL: 5000 IU/mL, 500 IU = 10 units on a U-100 syringe; 5,000 IU in 2 mL: 2500 IU/mL, 500 IU = 20 units on a U-100 syringe; 5,000 IU in 5 mL: 1000 IU/mL, 500 IU = 50 units on a U-100 syringe; 5,000 IU in 10 mL: 500 IU/mL, 500 IU = 100 units on a U-100 syringe; 10,000 IU in 1 mL: 10000 IU/mL, 500 IU = 5 units on a U-100 syringe; 10,000 IU in 2 mL: 5000 IU/mL, 500 IU = 10 units on a U-100 syringe; 10,000 IU in 5 mL: 2000 IU/mL, 500 IU = 25 units on a U-100 syringe; 10,000 IU in 10 mL: 1000 IU/mL, 500 IU = 50 units on a U-100 syringe.
Calculated from vial IU 5000, 10000; water mL 1, 2, 5, 10; label injection IU 500; u100 units per mL 100. Formula: IU/mL = vialIU / waterMl; syringe units = labelInjectionIU / (IU/mL) x 100
The 500 USP unit figure used above is one of the intramuscular regimens printed in the Novarel label for cryptorchidism, shown here as arithmetic input only.[3]
Sources
- 1Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
- 2BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
- 3NOVAREL (chorionic gonadotropin) for injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Ferring Pharmaceuticals label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
- 4Pregnyl (chorionic gonadotropin) for injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Organon LLC label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
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