hCG Dosage: Doses Studied, Units and Chart
What doses of hCG have been used in published research, how they convert to syringe units, and what is still unknown.
- Doses studied
- 6 studies
- with a stated dose, listed below
- Frequency
- twice weekly
- as used in studies
- Half-life
- pooled half-life 5.8 days
- injection (urinary and recombinant hCG), in people · Clinical endocrinology 2024, PMID 38446525
Dosing on the FDA label
Quoted from the approved product label. It applies to the approved product used as prescribed, not to compounded or research-chemical versions.
- Hypogonadotropic hypogonadism in males, regimen 1 · FDA label (Novarel)
- Hypogonadotropic hypogonadism in males, regimen 2 · FDA label (Novarel)
- Prepubertal cryptorchidism · FDA label (Novarel)
- Label statement on obesity (not an approved use) · FDA label (Novarel)
- Hypogonadotropic hypogonadism in males, regimen 1 · FDA label (Pregnyl)
- Hypogonadotropic hypogonadism in males, regimen 2 · FDA label (Pregnyl)
- Label statement on obesity (not an approved use) · FDA label (Pregnyl)
Doses used in published studies
Each dose below is quoted from a study abstract, strongest design first. Animal doses are labelled and do not translate directly to people. None of them is a recommendation.
| Dose | Frequency and route | Study type | Source |
|---|---|---|---|
| 1500 IU or 5000 IU urinary; 62.5 or 250 microg recombinant | injection | Human RCT | Clinical endocrinology 2024, PMID 38446525 |
| low-dose hCG 500 U vs 2000 U three times per week, plus FSH 150 U | injection | Human RCTn = 30 | Endocrine practice 2024, PMID 39025301 |
| 5000 IU hCG twice weekly (n = 94) vs clomiphene 50 mg (n = 95) vs both (n = 94) | twice weekly · injection · 3 months | Human RCTn = 282 | BJU international 2018, PMID 29772111 |
| hCG 2000 U twice weekly with uFSH 75 U three times weekly (continual or sequential) | injection · 18 months | Human RCTn = 67 | The Journal of clinical endocrinology and metabolism 2015, PMID 25825944 |
| 250 or 750 microg recombinant hCG, single dose | injection | Human RCT | Clinical endocrinology 2009, PMID 19170708 |
| 5000 IU (250 microg) recombinant hCG | twice weekly · subcutaneous self-injection · 3 months | Human RCTn = 40 | The Journal of clinical endocrinology and metabolism 2002, PMID 12107212 |
Before anyone considers it
- hCG is FDA approved (prescription only); research-chemical versions are not the approved drug.
- Compounded and research-chemical versions are not the approved product and are not checked by the FDA for identity, purity or dose.
- Reconstitution math (mg vs mcg, units vs mL) is the most asked question in peptide forums. Check every number twice.
- People who are pregnant, breastfeeding, or have a chronic condition need medical advice first.
Common questions
Is hCG FDA approved?
hCG is FDA approved (prescription only). Products sold as research chemicals are not the approved drug and are not checked by the FDA.
More on hCG
Side effectsWhat labels and studies report, and what is unknown.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.Legal statusFDA, compounding and WADA status with dates.How to injectSites, syringe types and hygiene, step by step.Half-lifeWhat is measured, by route, and what is not.
Sources
- 1Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
- 2BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
- 3NOVAREL ® (chorionic gonadotropin) for injection, for intramuscular use Initial U.S. Approval: 1974FDA label (Novarel), DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026
- 4Pregnyl ® (chorionic gonadotropin) for injectionFDA label (Pregnyl), DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026
- 5Single and multi-dose pharmacology of recombinant and urinary human chorionic gonadotrophin in men.Clinical endocrinology · 2024PMID 38446525Accessed 2 Oct 2026
- 6Effect of Combined Low Dose Human Gonadotropic Hormone, Follicle Stimulating Hormone, and Testosterone Therapy (LFT Regimen) Versus Conventional High Dose Human Gonadotropic Hormone and Follicle Stimulating Hormone on Spermatogenesis and Biomarkers in Men With Hypogonadotropic Hypogonadism.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2024PMID 39025301Accessed 2 Oct 2026
- 7Clomiphene citrate and human chorionic gonadotropin are both effective in restoring testosterone in hypogonadism: a short-course randomized study.BJU international · 2018PMID 29772111Accessed 2 Oct 2026
- 8Sequential Versus Continual Purified Urinary FSH/hCG in Men With Idiopathic Hypogonadotropic Hypogonadism.The Journal of clinical endocrinology and metabolism · 2015PMID 25825944Accessed 2 Oct 2026
- 9Effects of recombinant human LH and hCG on serum and urine LH and androgens in men.Clinical endocrinology · 2009PMID 19170708Accessed 2 Oct 2026
- 10A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency.The Journal of clinical endocrinology and metabolism · 2002PMID 12107212Accessed 2 Oct 2026
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