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Retatrutide 15 mg Vial: Reconstitution and Dosing Chart

How much bacteriostatic water to add to a 15 mg vial of Retatrutide, the concentration you get, and a full dose-to-units chart.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureGLP-1 / GIP / glucagon triple agonistUpdated
Vial size
15 mg
With 2 mL water
7.5 mg/mL
common choice
10 units contain
0.75 mg
at 2 mL, U-100
Whole vial
200 units
2 mL on a U-100 scale

How much water to add

Bacteriostatic water only changes the concentration, not the amount of Retatrutide in the vial. More water means more units per dose (easier to read), less water means fewer.

Retatrutide 15 mg vial: concentration by water added
Water addedConcentration10 units contain1 mg isWhole vial
1 mL15 mg/mL1.5 mg6.7 u100 u
2 mL7.5 mg/mL0.75 mg13.3 u200 u
2.5 mL6 mg/mL0.6 mg16.7 u250 u
3 mL5 mg/mL0.5 mg20 u300 u

Calculator and full dosing table

Preset to the 15 mg vial. Change any value; the table below the result updates with it.

1Vial size
2Bacteriostatic water added
3Dose per injection
4Syringe (U-100)
Draw to
26.67units
= 0.27 mL on a 1 mL U-100 insulin syringe
15 mg vial2 mL water2 mg dose
Concentration
7.5 mg/mL
Doses per vial
7
Weeks (1 dose/wk)
7
Math only. It does not recommend a dose.

26.67 units (0.27 mL) on a 1 mL U-100 syringe: 2 mg from a 15 mg vial + 2 mL water (Retatrutide).

Dosing table for a 15 mg vial

Syringe units (U-100) for each dose, by how much bacteriostatic water you add.

Retatrutide: U-100 syringe units per dose for a 15 mg vial
Dose1 mL water2 mL water2.5 mL water3 mL water
0.5 mg3.336.678.3310
1 mg6.6713.3316.6720
2 mg13.3326.6733.3340
4 mg26.6753.3366.6780
6 mg4080100120
8 mg53.33106.67133.33160
10 mg66.67133.33166.67200
12 mg80160200240

How the math works

Concentration is the vial's milligrams divided by the water you add. Volume to draw is your dose divided by that concentration. On a U-100 syringe, 1 mL is 100 units, so units = mL × 100.

15 mg ÷ 2 mL = 7.5 mg/mL
2 mg ÷ 7.5 mg/mL = 0.27 mL
0.27 mL × 100 = 26.67 units
26.67 units · 0.27 mL · 2 mg from 15 mg + 2 mL
Math only. The amounts in these tables are reference values for the arithmetic, not dose recommendations.

Common questions

How much water goes in a 15 mg vial of Retatrutide?

That choice only changes the concentration. With 2 mL, a 15 mg vial is 7.5 mg/mL; with 1 mL it is 15 mg/mL. Less water means fewer units per dose and harder-to-read marks for small doses.

How many units is 1 mg from a 15 mg vial?

With 2 mL of water, 1 mg is 13.3 units on a U-100 syringe. With other water amounts, see the table.

How many doses are in a 15 mg vial?

Divide the vial size by the dose (in the same unit). The calculator on this page shows the number of whole doses for any dose you pick.

More on Retatrutide

Sources

  1. 1Triple-Hormone-Receptor Agonist Retatrutide for Obesity: A Phase 2 Trial (Jastreboff AM et al.)New England Journal of Medicine · 2023PMID 37366315Accessed 2 Oct 2026
  2. 2Retatrutide, a Triple Hormone Receptor Agonist, for Treatment of Obesity (TRIUMPH-1; Jastreboff AM et al.)New England Journal of Medicine · 2026PMID 42814954Accessed 2 Oct 2026
  3. 3A Phase 2 Study of Once-Weekly LY3437943 Compared With Placebo in Participants Who Have Obesity or Are Overweight With Weight-Related Comorbidities (NCT04881760; arms and posted results)ClinicalTrials.gov (U.S. National Library of Medicine) · 2021clinicaltrials.govAccessed 2 Oct 2026
  4. 4Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
  5. 5BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026

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