Does AOD-9604 work?
Unknown in people. A drug profile says only that phase IIa trials were underway by February 2002.
HGH fragment analogUpdated
Short answer
Unknown in people. A drug profile says only that phase IIa trials were underway by February 2002.[1]
In rats, AOD-9604 cut body weight gain by over 50% against controls over 19 days; this is animal work.[2]
Other animal findings
In obese mice, AOD-9604 and growth hormone both reduced weight gain, with raised fat oxidation.[3]
A rabbit knee osteoarthritis study reported better cartilage regeneration with joint injections, again an animal result.[4]
More on AOD-9604
Sources
- 1AOD-9604 Metabolic.Current opinion in investigational drugs (London, England : 2000) · 2004PMID 15134286Accessed 2 Oct 2026
- 2Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone.Hormone research · 2000PMID 11146367Accessed 2 Oct 2026
- 3Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment.International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity · 2001PMID 11673763Accessed 2 Oct 2026
- 4Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model.Annals of clinical and laboratory science · 2015PMID 26275694Accessed 2 Oct 2026
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