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IGF-1 LR3 Side Effects: What Studies and Users Report

What FDA labels and clinical studies report for IGF-1 LR3, how strong that evidence is, and what is still unknown.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureIGF-1 analogUpdated

Side effects reported in studies

Side effects reported in published studies, strongest design first. Frequencies are quoted as the source gives them; animal results are labelled.

Side effects of IGF-1 LR3 in labels and published studies
Side effectHow commonStudy typeSource
Increased tumour growth“Tumour growth was increased by the IGFs, especially by LR3-IGF-I, even though these peptides did not promote growth of the adenocarcinoma in cell culture.”Frequency not statedAnimal · rat (not a human result)The Biochemical journal 1994, PMID 8053901

What is not known

  • How common each effect is at the doses people use outside of studies.
  • Effects that take longer to appear than the length of the published studies.
  • How IGF-1 LR3 interacts with other medicines and supplements.
  • Whether research-grade products, which are not checked by the FDA, behave like the material used in studies.

When to get medical help

Get urgent care for: trouble breathing, swelling of the face or throat, a widespread rash, severe or lasting stomach pain, fainting, or an injection site that becomes hot, red and spreading.

This is not a complete list. A doctor or pharmacist can help you judge whether a symptom is related.

Common questions

What are the side effects of IGF-1 LR3?

Studies we summarise reported increased tumour growth. The table on this page gives how often each happened and links each source.

Is IGF-1 LR3 safe?

IGF-1 LR3 has an FDA-approved label that lists its known risks. That label covers the approved product used as prescribed, not compounded or research-chemical versions.

Is IGF-1 LR3 banned in sport?

Yes. Prohibited by WADA (S2.3). Tested athletes should not use it.

More on IGF-1 LR3

DosageDoses used in published studies, with the source for each.CalculatorVial, water and dose to syringe units.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.How to injectSites, syringe types and hygiene, step by step.1 mg vialConcentration and unit tables for the 1 mg size.

Sources

  1. 1Effects of insulin and insulin-like growth factors on protein and energy metabolism in tumour-bearing rats.The Biochemical journal · 1994PMID 8053901Accessed 2 Oct 2026

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