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Ipamorelin Side Effects: What Studies and Users Report

What FDA labels and clinical studies report for Ipamorelin, how strong that evidence is, and what is still unknown.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureGHRP (ghrelin receptor agonist)Updated

Side effects reported in studies

Side effects reported in published studies, strongest design first. Frequencies are quoted as the source gives them; animal results are labelled.

Side effects of Ipamorelin in labels and published studies
Side effectHow commonStudy typeSource
Any treatment-emergent adverse event87.5% ipamorelin vs 94.8% placeboHuman RCTn = 117International journal of colorectal disease 2014, PMID 25331030
Tolerability“Ipamorelin 0.03-mg/kg twice daily for up to 7 days was well tolerated.”Frequency not statedHuman RCTn = 117International journal of colorectal disease 2014, PMID 25331030

What is not known

  • How common each effect is at the doses people use outside of studies.
  • Effects that take longer to appear than the length of the published studies.
  • How Ipamorelin interacts with other medicines and supplements.
  • Whether research-grade products, which are not checked by the FDA, behave like the material used in studies.

When to get medical help

Get urgent care for: trouble breathing, swelling of the face or throat, a widespread rash, severe or lasting stomach pain, fainting, or an injection site that becomes hot, red and spreading.

This is not a complete list. A doctor or pharmacist can help you judge whether a symptom is related.

Common questions

What are the side effects of Ipamorelin?

Studies we summarise reported any treatment-emergent adverse event, tolerability. The table on this page gives how often each happened and links each source.

Is Ipamorelin safe?

Ipamorelin has an FDA-approved label that lists its known risks. That label covers the approved product used as prescribed, not compounded or research-chemical versions.

Is Ipamorelin banned in sport?

Yes. Prohibited by WADA (S2.2.4). Tested athletes should not use it.

More on Ipamorelin

DosageDoses used in published studies, with the source for each.CalculatorVial, water and dose to syringe units.Legal statusFDA, compounding and WADA status with dates.For menopauseWhat research says about Ipamorelin for menopause.

Sources

  1. 1Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients.International journal of colorectal disease · 2014PMID 25331030Accessed 2 Oct 2026

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