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hCG and HGH Together: What Is Known

hCG and HGH taken together: what each one is, how each is regulated, and what is known about combining them.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureUpdated
GonadotropinFDA approved (prescription only)hCGGonadotropin FDA-approved for specific uses; the Novarel label states hCG has not been demonstrated to be effective adjunctive therapy in the treatment of obesity.[10]OtherRecombinant growth hormoneFDA approved (prescription only)HGHRecombinant human growth hormone, FDA-approved by prescription; in a randomized trial, 4 weeks of supraphysiological dosing did not improve power output or oxygen uptake.[11]Growth hormone
Interaction notes

Timing, interactions and safety

Evidence for the combination

No studies tested these together (PubMed search: 39 results, 2 Oct 2026).

We have no sourced data on taking these two together. Ask the prescriber who manages both.
Each component

Side by side

Showing 7 of 11 fields where the two differ. FDA status, PCAC vote, Jul 2026, Evidence strength, US searches per month are the same or both unknown.

FieldhCGHGH
ClassGonadotropinRecombinant growth hormone
Also calledhuman chorionic gonadotropinGH, growth hormone, generic HGH, IU
CategoryOtherGrowth hormone
WADAProhibited by WADA (S2.2.1)Chorionic gonadotrophin (hCG) is prohibited for male athletes (S2.2.1, testosterone-stimulating peptides). The list limits this class to males.Prohibited by WADA (S2.2.3)Growth hormone and its analogues and fragments are prohibited at all times (S2.2.3).
Half-lifepooled half-life 5.8 daysinjection (urinary and recombinant hCG) · Clinical endocrinology 2024, PMID 384465250.4 hours IV; 3.0 hours subcutaneousintravenous (normal adults); subcutaneous (GHD adults), Genotropin · FDA label (Genotropin)
Human studies we summarised10 human (9 randomized or controlled) of 15 summarised13 human (13 randomized or controlled) of 20 summarised
Typical study doses
Related tools

hCG vs HGH

Choosing between the two rather than combining them? The comparison lines them up field by field.

Open the comparison
ComparisonHGH vs hCG

What people search

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  • hgh and hcg together20/mo
  • hcg and hgh together20/mo

US monthly searches, Google Keyword Planner, Oct 2026. Shown so you can see which questions this page answers.

Sources

  1. 1World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
  2. 2Single and multi-dose pharmacology of recombinant and urinary human chorionic gonadotrophin in men.Clinical endocrinology · 2024PMID 38446525Accessed 2 Oct 2026
  3. 3Effect of Combined Low Dose Human Gonadotropic Hormone, Follicle Stimulating Hormone, and Testosterone Therapy (LFT Regimen) Versus Conventional High Dose Human Gonadotropic Hormone and Follicle Stimulating Hormone on Spermatogenesis and Biomarkers in Men With Hypogonadotropic Hypogonadism.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2024PMID 39025301Accessed 2 Oct 2026
  4. 4Clomiphene citrate and human chorionic gonadotropin are both effective in restoring testosterone in hypogonadism: a short-course randomized study.BJU international · 2018PMID 29772111Accessed 2 Oct 2026
  5. 5GENOTROPIN (SOMATROPIN) KIT [PFIZER LABORATORIES DIV PFIZER INC]FDA label (Genotropin), DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026
  6. 6Effect of growth hormone on aging connective tissue in muscle and tendon: gene expression, morphology, and function following immobilization and rehabilitation.Journal of applied physiology (Bethesda, Md. : 1985) · 2014PMID 24235105Accessed 2 Oct 2026
  7. 7Impact of GH replacement therapy on sleep in adult patients with GH deficiency of pituitary origin.European journal of endocrinology · 2013PMID 23447518Accessed 2 Oct 2026
  8. 8Local administration of growth hormone stimulates tendon collagen synthesis in elderly men.Journal of applied physiology (Bethesda, Md. : 1985) · 2012PMID 22961272Accessed 2 Oct 2026
  9. 9PubMed search: (("human chorionic gonadotropin"[tiab] OR "chorionic gonadotropin"[tiab] OR "chorionic gonadotrophin"[tiab] OR hCG[tiab] OR choriogonadotropin[tiab]) NOT (pregnan*[tiab] OR trophoblast*[tiab] OR choriocarcinoma[tiab] OR "germ cell"[tiab] OR hydatidiform[tiab] OR "embryo transfer"[tiab] OR oocyte*[tiab] OR "in vitro fertilization"[tiab] OR IVF[tiab] OR "ovarian stimulation"[tiab] OR "ovulation induction"[tiab] OR "ovarian hyperstimulation"[tiab] OR equine[tiab] OR eCG[tiab] OR "pregnant mare"[tiab])) AND (somatropin[tiab] OR "recombinant human growth hormone"[tiab] OR "recombinant growth hormone"[tiab] OR rhGH[tiab] OR "growth hormone therapy"[tiab] OR "growth hormone treatment"[tiab] OR "growth hormone replacement"[tiab] OR "growth hormone administration"[tiab] OR "GH therapy"[tiab] OR "GH treatment"[tiab] OR "GH replacement"[tiab] OR "GH administration"[tiab] OR "growth hormone injection"[tiab] OR "growth hormone injections"[tiab] OR "growth hormone supplementation"[tiab])PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  10. 10NOVAREL ® (chorionic gonadotropin) for injection, for intramuscular use Initial U.S. Approval: 1974FDA label, DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026
  11. 11Short-term administration of supraphysiological recombinant human growth hormone (GH) does not increase maximum endurance exercise capacity in healthy, active young men and women with normal GH-insulin-like growth factor I axes.The Journal of clinical endocrinology and metabolism · 2005PMID 15784718Accessed 2 Oct 2026

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