VIP
Vasoactive intestinal peptide. VIP is Not FDA approved · compounded or research; research-chemical versions are not the approved drug.
Also called:vasoactive intestinal peptide
Medically reviewed by Juan Pablo Frías, MD · · DisclosureUpdated Strongest evidence: Human RCT evidence, 4 of 4
Key facts
How we verify- Class
- Vasoactive intestinal peptide
- Also called
- vasoactive intestinal peptide
- Half-life
- Not found
- No published half-life found (PubMed search, 2 Oct 2026)
- FDA status
- Not FDA approved · compounded or research
- No approved product found
- WADA
- Unclear
- Not named on the 2026 list
Everything on VIP
VIP guides
Evidence at a glance
Human and animal counts are PubMed records from our evidence ledger (search counts, not studies we reviewed). The grade is the strongest design among the studies we summarised for that goal: a human randomized trial outweighs any number of animal studies.
| Condition | Human studies | Animal studies | Studies we summarised | Evidence grade |
|---|---|---|---|---|
| Any condition (no goal ledger yet) | Not in our ledger | Not in our ledger | 12 | Human RCT evidence, 4 of 4Medical principles and practice 2025, PMID 39870064 |
Grades follow our evidence scale. Summarised studies come from our evidence file, each quote checked against the abstract or label.
Common questions
Is VIP FDA approved?
VIP is Not FDA approved · compounded or research. Products sold as research chemicals are not the approved drug and are not checked by the FDA.
Sources
- 1US search volume and year-over-year trend, Google Keyword Planner export (Jun–Aug 2026 vs 2025)Peptigraph research · 2026peptigraph.com/methodology/Accessed 1 Oct 2026
- 2World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
- 3United States: No FDA-approved product found: Drugs@FDA (openFDA) search for active ingredient "VIP" returned no matches on 2 Oct 2026.U.S. Food and Drug Administration · 2026api.fda.govAccessed 2 Oct 2026
- 4US compounding: Vasoactive intestinal peptide is listed in FDA's 503A category 1 (bulk drug substances under evaluation).U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
- 5Inhaled Aviptadil Is a New Hope for Recovery of Lung Damage due to COVID-19.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025PMID 39870064Accessed 2 Oct 2026
- 6PubMed search: aviptadil[tiab] (30 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 7PubMed search: aviptadil[tiab] AND (randomized[tiab] OR "clinical trial"[pt]) (6 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 8PubMed search: (aviptadil[tiab] OR "vasoactive intestinal peptide"[tiab] OR "vasoactive intestinal polypeptide"[tiab]) AND (randomized[tiab] OR trial[tiab] OR patients[tiab]) (1509 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 9PubMed search: (aviptadil[tiab] OR "vasoactive intestinal peptide"[tiab]) AND (half-life[tiab] OR pharmacokinetic*[tiab]) (70 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 10PubMed search: "vasoactive intestinal peptide"[tiab] AND (CIRS[tiab] OR "inflammatory response syndrome"[tiab] OR mycotoxin*[tiab] OR "water-damaged"[tiab]) (4 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 11PubMed search: "vasoactive intestinal peptide"[tiab] AND ("clinical trial"[pt] OR randomized[tiab]) AND (inhal*[tiab] OR intranasal[tiab] OR sarcoid*[tiab] OR "pulmonary hypertension"[tiab] OR ARDS[tiab]) (15 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
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