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Epitalon Dosage: Doses Studied, Units and Chart

What doses of Epitalon have been used in published research, how they convert to syringe units, and what is still unknown.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureTetrapeptideUpdated
Doses studied
3 studies
with a stated dose, listed below
Frequency
Varies by study
as used in studies
Half-life
Not found
No published half-life found (PubMed search, 2 Oct 2026)
Vial sizes sold
10 mg, 50 mg, 100 mg

Doses used in published studies

Each dose below is quoted from a study abstract, strongest design first. Animal doses are labelled and do not translate directly to people. None of them is a recommendation.

Doses of Epitalon used in published studies
DoseFrequency and routeStudy typeSource
0.1 microg5 times a week · injection · 6.5 monthsAnimal · mouse (not a human result)In vivo 2006, PMID 16634527
1mkg/mouse5 times a week monthly · subcutaneousAnimal · mouse (not a human result)Voprosy onkologii 2005, PMID 15909815
1.0 microg/mouse (approximately 30-40 microg/kg)5 consecutive days every month · subcutaneous · from 3 months of age until natural deathAnimal · mouse (not a human result)n = 108Biogerontology 2003, PMID 14501183

Dose to syringe units

For a 10 mg vial mixed with 2 mL of bacteriostatic water (5 mg/mL), on a U-100 syringe. These are reference amounts for the math, not suggested doses.

0.5 mg
10 u
1 mg
20 u
2 mg
40 u
5 mg
100 u
Use your own vial and water

Before anyone considers it

  • Epitalon is not FDA approved for any use.
  • Products sold as research chemicals are not checked by the FDA for identity, purity or dose.
  • Reconstitution math (mg vs mcg, units vs mL) is the most asked question in peptide forums. Check every number twice.
  • People who are pregnant, breastfeeding, or have a chronic condition need medical advice first.

Common questions

How many units is 2 mg of Epitalon?

It depends on the water added. A 10 mg vial with 2 mL of water gives 5 mg/mL, so 2 mg is 40 units on a U-100 syringe. Use the calculator for other mixes.

Is Epitalon FDA approved?

No. Epitalon is not FDA approved for any use. The FDA removed it from Category 2 on 15 Apr 2026. Its advisory committee voted 7–5 in July 2026 to add it to the 503A compounding list. That vote is not final.

More on Epitalon

ResultsStudy outcomes and when they were measured.CalculatorVial, water and dose to syringe units.PricePrice per mg and per week from dated listings. No vendor links.

Sources

  1. 1Certain bulk drug substances for use in compounding that may present significant safety risks (Category 2; 'nominated but withdrawn' table, content current as of 22 Apr 2026)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  2. 2Pharmacy Compounding Advisory Committee meeting, 23–24 Jul 2026 (agenda and materials)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  3. 3Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
  4. 4BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
  5. 5Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice.In vivo (Athens, Greece) · 2006PMID 16634527Accessed 2 Oct 2026
  6. 6[Effect of epitalon and melatonin on life span and spontaneous carcinogenesis in senescence accelerated mice (SAM)].Voprosy onkologii · 2005PMID 15909815Accessed 2 Oct 2026
  7. 7Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice.Biogerontology · 2003PMID 14501183Accessed 2 Oct 2026
  8. 8PubMed search: (epitalon[tiab] OR epithalon[tiab] OR epithalamin[tiab]) (165 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  9. 9PubMed search: (epitalon[tiab] OR epithalon[tiab] OR epithalamin[tiab]) AND (humans[mh] OR patients[tiab] OR randomized[tiab]) (58 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  10. 10PubMed search: (epitalon[tiab] OR epithalon[tiab] OR epithalamin[tiab]) AND (half-life[tiab] OR pharmacokinetic*[tiab]) (0 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  11. 11PubMed search: epitalon[tiab] AND (mice[tiab] OR rats[tiab] OR "life span"[tiab] OR lifespan[tiab]) (31 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026

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