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Peptides for Muscle growth

The peptides people most often research for muscle growth, with how much evidence exists for each. A long list does not mean any of them is proven to work in people.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureUpdated
Peptides listed
8
With human trials
6
FDA approved (any use)
6
Searches per month
89,990
Showing 8 peptides · ordered by search interest for this goal
  1. CJC-1295GHRH analogHuman observational evidence, 3 of 4Substance use & misuse 2016, PMID 26771670Human1Animal1Summarised2Not FDA approved · research chemicalFor muscle growthOverview
  2. CJC-1295 + IpamorelinGHRH + GHRP blendHuman observational evidence, 3 of 4CJC-1295: Substance use & misuse 2016, PMID 26771670Human1Animal0Summarised6Not FDA approved · research blendFor muscle growthOverview
  3. SermorelinGHRH analogHuman observational evidence, 3 of 4American journal of men's health 2017, PMID 28830317Human2Animal0Summarised3Compounded by prescriptionFor muscle growthOverview
  4. IGF-1 LR3IGF-1 analogAnimal evidence, 2 of 4American journal of physiology. Endocrinology and metabolism 2025, PMID 39679943Human0Animal6Summarised8Not FDA approved · research chemicalFor muscle growthOverview
  5. HGHRecombinant growth hormoneHuman RCT evidence, 4 of 4Journal of applied physiology 2014, PMID 24235105Human767Animal80Summarised9FDA approved (prescription only)For muscle growthOverview
  6. EnclomipheneSERM (not a peptide)No study with an outcome for muscle growthPubMed search, 2 Oct 2026Human0Animal0Summarised0Not FDA approved · compoundedFor muscle growthOverview
  7. hCGGonadotropinHuman RCT evidence, 4 of 4The Journal of clinical endocrinology and metabolism 2002, PMID 12107212Human19Animal2Summarised2FDA approved (prescription only)For muscle growthOverview
  8. MOTS-cMitochondrial-derived peptideHuman RCT evidence, 4 of 4Medicine and science in sports and exercise 2025, PMID 40674654Human6Animal2Summarised4PCAC voted 7–5 for 503A (Jul 2026)For muscle growthOverview
Read this first

What this list does not show

Search demand tells you what people are curious about, not what works. Read each peptide's evidence before anything else.

Search interest is not evidence

This list follows what people search for and discuss. It says nothing about how well any peptide works.

Animal results may not carry over

Doses, routes and effects seen in rodents or cell dishes often have no tested human equivalent.

Approval covers specific uses

An FDA approval applies to the conditions and doses on the label, not to every goal a drug is searched with.

Combinations are a separate question

Blends and stacks put several peptides together. Evidence for one peptide is not evidence for the mix.
Related goals

Explore nearby goals

What people search

  • muscle growth peptides60,500/mo
  • best peptides for muscle growth18,100/mo
  • peptides for muscle gain8,100/mo
  • best peptides for muscle gain1,300/mo
  • peptide stack for muscle growth590/mo
  • muscle gain peptides590/mo

US monthly searches, Google Keyword Planner, Oct 2026. Shown so you can see which questions this page answers.

Sources

  1. 1Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions.Substance use & misuse · 2016PMID 26771670Accessed 2 Oct 2026
  2. 2Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels.American journal of men's health · 2017PMID 28830317Accessed 2 Oct 2026
  3. 3IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep.American journal of physiology. Endocrinology and metabolism · 2025PMID 39679943Accessed 2 Oct 2026
  4. 4Effect of growth hormone on aging connective tissue in muscle and tendon: gene expression, morphology, and function following immobilization and rehabilitation.Journal of applied physiology (Bethesda, Md. : 1985) · 2014PMID 24235105Accessed 2 Oct 2026
  5. 5A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency.The Journal of clinical endocrinology and metabolism · 2002PMID 12107212Accessed 2 Oct 2026
  6. 6Repeated Heat Stress Modulates the Levels of the Mitokines MOTS-C and FGF21 in Active Men during Calf Muscle Immobilization.Medicine and science in sports and exercise · 2025PMID 40674654Accessed 2 Oct 2026
  7. 7PubMed search: enclomiphene[tiab] OR enclomifene[tiab] OR "trans-clomiphene"[tiab] (98 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  8. 8PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt]) (9 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  9. 9PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (hypogonadism[tiab] OR testosterone[tiab]) AND humans[mh] (17 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  10. 10PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (half-life[tiab] OR pharmacokinetic*[tiab]) (5 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026

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