Skip to content
Peptigraph home

Enclomiphene

SERM (not a peptide). Enclomiphene is Not FDA approved · compounded; research-chemical versions are not the approved drug.

Also called:enclo
Medically reviewed by Juan Pablo Frías, MD · · DisclosureUpdated Strongest evidence: Human RCT evidence, 4 of 4
StatusNot FDA approved · compoundedProhibited by WADA (S4.2)Full legal history

Key facts

How we verify
Class
SERM (not a peptide)
Not a peptide
Also called
enclo
Half-life
Not found
No published half-life found (PubMed search, 2 Oct 2026)
FDA status
Not FDA approved · compounded
No approved product found
WADA
Prohibited (S4.2)
In and out of competition
Everything on Enclomiphene

Enclomiphene guides

DosageDoses used in published studies, with the source for each.Side effectsWhat labels and studies report, and what is unknown.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.Legal statusFDA, compounding and WADA status with dates.Half-lifeWhat is measured, by route, and what is not.StoragePowder and mixed vials: temperature and shelf life.For muscle growthWhat research says about Enclomiphene for muscle growth.For testosteroneWhat research says about Enclomiphene for testosterone.For weight lossWhat research says about Enclomiphene for weight loss.

Evidence at a glance

Human and animal counts are PubMed records from our evidence ledger (search counts, not studies we reviewed). The grade is the strongest design among the studies we summarised for that goal: a human randomized trial outweighs any number of animal studies.

Enclomiphene: studies by condition
ConditionHuman studiesAnimal studiesStudies we summarisedEvidence grade
Muscle growth000No graded study for this goal
Testosterone1458Human RCT evidence, 4 of 4BJU international 2016, PMID 26496621
Weight lossNot in our ledgerNot in our ledger0No graded study for this goal

Grades follow our evidence scale. Summarised studies come from our evidence file, each quote checked against the abstract or label.

Compared with

EnclomiphenevshCGSERM (not a peptide) next to gonadotropin: evidence, dosing and legal status side by side.FDA approved (prescription only)Read the comparison →EnclomiphenevsSermorelinSERM (not a peptide) next to ghrh analog: evidence, dosing and legal status side by side.Compounded by prescriptionRead the comparison →EnclomiphenevsKisspeptin-10SERM (not a peptide) next to gnrh stimulator: evidence, dosing and legal status side by side.Not FDA approved · research chemicalRead the comparison →

Common stacks

Enclomiphene is often sold pre-mixed or combined with other peptides. A few of these pairs appear together in published studies; each stack page lists what was tested, and the pages below cover the math and what each part has been studied for.

Enclomiphene + hCGEnclomiphene + Sermorelin

Common questions

Is Enclomiphene FDA approved?

Enclomiphene is Not FDA approved · compounded. Products sold as research chemicals are not the approved drug and are not checked by the FDA.

Is Enclomiphene a peptide?

No. It is a serm. It is listed here because people research it alongside peptides.

Is Enclomiphene banned in sport?

Yes. Prohibited by WADA (S4.2), so it is prohibited at all times for tested athletes.

Sources

  1. 1US search volume and year-over-year trend, Google Keyword Planner export (Jun–Aug 2026 vs 2025)Peptigraph research · 2026peptigraph.com/methodology/Accessed 1 Oct 2026
  2. 2World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
  3. 3United States: No FDA-approved product found: Drugs@FDA (openFDA) search for active ingredient "enclomiphene" returned no matches on 2 Oct 2026.U.S. Food and Drug Administration · 2026api.fda.govAccessed 2 Oct 2026
  4. 4US compounding: Enclomiphene citrate is listed in FDA's 503A category 1 (bulk drug substances under evaluation).U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  5. 5Oral enclomiphene citrate raises testosterone and preserves sperm counts in obese hypogonadal men, unlike topical testosterone: restoration instead of replacement.BJU international · 2016PMID 26496621Accessed 2 Oct 2026
  6. 6PubMed search: enclomiphene[tiab] OR enclomifene[tiab] OR "trans-clomiphene"[tiab] (98 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  7. 7PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt]) (9 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  8. 8PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (hypogonadism[tiab] OR testosterone[tiab]) AND humans[mh] (17 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  9. 9PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (half-life[tiab] OR pharmacokinetic*[tiab]) (5 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026

Found an error? Report a correction.