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Enclomiphene Dosage: Doses Studied, Units and Chart

What doses of Enclomiphene have been used in published research, how they convert to syringe units, and what is still unknown.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureSERM (not a peptide)Updated
Doses studied
5 studies
with a stated dose, listed below
Frequency
daily
as used in studies
Half-life
Not found
No published half-life found (PubMed search, 2 Oct 2026)

Doses used in published studies

Each dose below is quoted from a study abstract, strongest design first. Animal doses are labelled and do not translate directly to people. None of them is a recommendation.

Doses of Enclomiphene used in published studies
DoseFrequency and routeStudy typeSource
two doses of enclomiphene citrate vs testosterone gel (AndroGel 1.62%)daily · oral · 16 weeksHuman RCTBJU international 2016, PMID 26496621
6.25, 12.5 or 25 mgdaily · oral · six weeksHuman RCTn = 48BJU international 2013, PMID 23875626
50 mg daily (inadvertent; prescribed 25 mg)oralHuman case reportn = 1Cureus 2026, PMID 42741668
enclomiphene citrate 12.5-25 mg daily; clomiphene 12.5-50 mg dailyoral · 1.5-4 monthsMeta-analysisn = 292Andrology 2023, PMID 36604313
4 and 40 mg/kg/day enclomipheneoral gavageAnimal · mouse (not a human result)BJU international 2016, PMID 26220499

Before anyone considers it

  • Enclomiphene is Not FDA approved · compounded; research-chemical versions are not the approved drug.
  • Compounded and research-chemical versions are not the approved product and are not checked by the FDA for identity, purity or dose.
  • Reconstitution math (mg vs mcg, units vs mL) is the most asked question in peptide forums. Check every number twice.
  • People who are pregnant, breastfeeding, or have a chronic condition need medical advice first.

Common questions

Is Enclomiphene FDA approved?

Enclomiphene is Not FDA approved · compounded. Products sold as research chemicals are not the approved drug and are not checked by the FDA.

More on Enclomiphene

Side effectsWhat labels and studies report, and what is unknown.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.Legal statusFDA, compounding and WADA status with dates.Half-lifeWhat is measured, by route, and what is not.StoragePowder and mixed vials: temperature and shelf life.

Sources

  1. 1Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
  2. 2BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
  3. 3Oral enclomiphene citrate raises testosterone and preserves sperm counts in obese hypogonadal men, unlike topical testosterone: restoration instead of replacement.BJU international · 2016PMID 26496621Accessed 2 Oct 2026
  4. 4Testosterone Restoration by Enclomiphene Citrate in Men with Secondary Hypogonadism: Pharmacodynamics and Pharmacokinetics.BJU international · 2013PMID 23875626Accessed 2 Oct 2026
  5. 5Newly Detected Atrial Flutter After Enclomiphene Dose Escalation in a Patient With Prior Mitral Valve Repair and Chronic Immune Thrombocytopenia: A Case Report.Cureus · 2026PMID 42741668Accessed 2 Oct 2026
  6. 6Selective modulation of estrogen receptor in obese men with androgen deficiency: A systematic review and meta-analysis.Andrology · 2023PMID 36604313Accessed 2 Oct 2026
  7. 7Differential effects of isomers of clomiphene citrate on reproductive tissues in male mice.BJU international · 2016PMID 26220499Accessed 2 Oct 2026
  8. 8PubMed search: enclomiphene[tiab] OR enclomifene[tiab] OR "trans-clomiphene"[tiab] (98 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  9. 9PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt]) (9 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  10. 10PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (hypogonadism[tiab] OR testosterone[tiab]) AND humans[mh] (17 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  11. 11PubMed search: (enclomiphene[tiab] OR enclomifene[tiab]) AND (half-life[tiab] OR pharmacokinetic*[tiab]) (5 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026

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