Semaglutide 2 mg Vial: Reconstitution and Dosing Chart

How much bacteriostatic water to add to a 2 mg vial of Semaglutide, the concentration you get, and a full dose-to-units chart.

Medical review pendingGLP-1 agonistUpdated 20 Oct 2026

Vial size: 2 mg
With 2 mL water: 1 mg/mL; common choice
10 units contain: 0.1 mg; at 2 mL, U-100
Whole vial: 200 units; 2 mL on a U-100 scale

How much water to add

Bacteriostatic water only changes the concentration, not the amount of Semaglutide in the vial. More water means more units per dose (easier to read), less water means fewer.

Semaglutide 2 mg vial: concentration by water added
Water added	Concentration	10 units contain	1 mg is	Whole vial
1 mL	2 mg/mL	0.2 mg	50 u	100 u
2 mL	1 mg/mL	0.1 mg	100 u	200 u
2.5 mL	0.8 mg/mL	0.08 mg	125 u	250 u
3 mL	0.667 mg/mL	0.067 mg	150 u	300 u

Calculator and full dosing table

Preset to the 2 mg vial. Change any value; the table below the result updates with it.

1Vial size

2Bacteriostatic water added

3Dose per injection

4Syringe (U-100)

Draw to

100units

= 1 mL on a 1 mL U-100 insulin syringe

2 mg vial2 mL water1 mg dose

Concentration: 1 mg/mL
Doses per vial: 2
Weeks (1 dose/wk): 2

Math only. It does not recommend a dose.

Dosing table for a 2 mg vial

Syringe units (U-100) for each dose, by how much bacteriostatic water you add.

Semaglutide: U-100 syringe units per dose for a 2 mg vial
Dose	1 mL water	2 mL water	2.5 mL water	3 mL water
0.25 mg	12.5	25	31.25	37.5
0.5 mg	25	50	62.5	75
1 mg	50	100	125	150
1.5 mg	75	150	187.5	225
2 mg	100	200	250	300

How the math works

Concentration is the vial's milligrams divided by the water you add. Volume to draw is your dose divided by that concentration. On a U-100 syringe, 1 mL is 100 units, so units = mL × 100.

2 mg ÷ 2 mL = 1 mg/mL
1 mg ÷ 1 mg/mL = 1 mL
1 mL × 100 = 100 units

100 units · 1 mL · 1 mg from 2 mg + 2 mL

Math only. The amounts in these tables are reference values for the arithmetic, not dose recommendations.

Where the doses for a semaglutide vial of 2 mg come from

Ozempic label states: It contains 2 mg of semaglutide, and you can select doses of 0.25 mg or 0.5 mg.^[3]

Ozempic label states: Combination with metformin or metformin with sulfonylurea In a 40-week, double-blind trial (NCT03989232), 961 patients with type 2 diabetes currently treated with metformin with or without sulfonylurea treatment were randomized to OZEMPIC 2 mg or OZEMPIC 1 mg once weekly.^[3]

What a semaglutide vial of 2 mg gives

2 mg semaglutide vial (dose -> supply -> units at 1 / 2 / 3 mL of water): 0.2 mg -> 10 doses = 10 weeks -> 10 / 20 / 30 units; 0.25 mg -> 8 doses = 8 weeks -> 12.5 / 25 / 37.5 units; 0.5 mg -> 4 doses = 4 weeks -> 25 / 50 / 75 units; 1 mg -> 2 doses = 2 weeks -> 50 / 100 / 150 (over one 1 mL syringe) units; 1.7 mg -> 1 dose = 1 weeks, 0.3 mg left -> 85 / 170 (over one 1 mL syringe) / 255 (over one 1 mL syringe) units.

Calculated from vial mg 2; doses mg 0.2, 0.25, 0.5, 1, 1.7; dose sources quoted trial and label doses on this page or in the cached semaglutide sources; water mL 1, 2, 3; u100 units per mL 100; injections per week 1. Formula: full doses = floor(vialMg / doseMg); units = doseMg / (vialMg / waterMl) x 100; flag units < 5 or > 100

A 2 mg vial reconstituted in 1 / 2 / 3 mL gives 2 mg/mL, 1 mg/mL and 0.667 mg/mL.

Calculated from vial mg 2; water mL 1, 2, 3. Formula: mg/mL = vialMg / waterMl

Is 2 mg a labelled semaglutide strength

Against the labelled injectable pen totals, a 2 mg vial compares as follows: 2 mg is equal to a 2 mg vial, 4 mg is larger than a 2 mg vial, 8 mg is larger than a 2 mg vial, 9.6 mg is larger than a 2 mg vial.

Calculated from vial mg 2; labelled pen totals mg 2, 4, 8, 9.6. Formula: compare vialMg with each labelled pen total

No label cached for this page lists a 2 mg single-vial product; the cached Ozempic and Wegovy labels describe pens and prefilled syringes only.

Calculated from vial mg 2; labels checked Ozempic, Wegovy, Rybelsus and Ozempic tablets. Formula: search of the three cached labels for a 2 mg vial strength: none

Common questions

How much water goes in a 2 mg vial of Semaglutide?

That choice only changes the concentration. With 2 mL, a 2 mg vial is 1 mg/mL; with 1 mL it is 2 mg/mL. Less water means fewer units per dose and harder-to-read marks for small doses.

How many units is 1 mg from a 2 mg vial?

With 2 mL of water, 1 mg is 100 units on a U-100 syringe. With other water amounts, see the table.

How many doses are in a 2 mg vial?

Divide the vial size by the dose (in the same unit). The calculator on this page shows the number of whole doses for any dose you pick.

How many micrograms are in one unit of a 2 mg semaglutide vial?

In a 2 mg semaglutide vial, one U-100 unit holds 20 mcg at 1 mL, 10 mcg at 2 mL and 6.67 mcg at 3 mL.

Calculated from vial mg 2; water mL 1, 2, 3. Formula: mcg per unit = vialMg / waterMl x 10

More on Semaglutide

DosageDoses used in published studies, with the source for each.CalculatorVial, water and dose to syringe units.Side effectsWhat labels and studies report, and what is unknown.BenefitsClaimed benefits next to what published studies measured.How it worksTarget, mechanism and how long it acts, from the label or studies.OralStudies that gave Semaglutide as pills and capsules, and what is approved.

Sources

1Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
2BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
3OZEMPIC prescribing information (FDA label)FDA label, DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026

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