HGH for Testosterone: What the Evidence Shows
What human and animal studies show about HGH for testosterone, how strong that evidence is, and what is still unproven.
- Strongest evidence
- Human RCT
- Human studies
- 352
- PubMed records, our ledger
- Animal studies
- 50
- PubMed records, our ledger
- Studies we summarised
- 2
- with an outcome for testosterone
Evidence for testosterone
Each row is an outcome related to testosterone from a published study, strongest design first. Animal and cell results are labelled and are not human results. User reports are not counted as evidence here.
| Outcome | Result | Study type | Source |
|---|---|---|---|
| Lean mass and fat | Lean body mass increased with GH alone and with GH plus testosterone versus placebo; total body fat decreased only with the combination. | Human RCTn = 80 | The Journal of clinical endocrinology and metabolism 2006, PMID 16332938 |
| Protein synthesis in older adults | Low-dose GH increased protein synthesis in healthy aged women and men, and testosterone plus GH enhanced this in men (a whole-body protein-turnover measure). | Human RCT | Metabolism: clinical and experimental 2005, PMID 16125527 |
PubMed records for HGH and testosterone: 352 human, 50 animal (search counts, not studies we reviewed). Grades follow our .
How strong is it?
A human randomized trial outweighs any number of animal studies. Animal and cell results show a mechanism worth testing, not that it works in people.
What a testosterone test measures
MedlinePlus explains that a testosterone levels test measures the amount of the hormone testosterone in a blood sample.[3]
Trials that gave GH alongside testosterone
In the 80-man trial, testosterone was a randomized treatment arm, so GH and testosterone were compared and combined rather than GH being tested to raise testosterone.[1]
In the study of older men and women, testosterone enanthate was given to men as a separate arm and raised testosterone levels.[2]
What is not shown
Neither of the 2 abstracts cited here reports GH raising a person's own testosterone level; testosterone changes appear only in the arms that were given testosterone.
Calculated from abstracts cited 2; abstracts reporting gh raising testosterone 0. Formula: abstracts showing GH raising testosterone = 0 of 2
Size of the literature
The goal-ledger query run 2026-10-02 for testosterone terms found 352 human-only and 50 animal-only PubMed records mentioning growth hormone terms.
Calculated from goal testosterone; peptide hgh; method pubmed-tiab-v1; date 2026-10-02; query (somatropin[tiab] OR "recombinant human growth hormone"[tiab] OR "recombinant growth hormone"[tiab] OR rhGH[tiab] OR "growth hormone therapy"[tiab] OR "growth hormone treatment"[tiab] OR "growth hormone replacement"[tiab] OR "growth hormone administration"[tiab] OR "GH therapy"[tiab] OR "GH treatment"[tiab] OR "GH replacement"[tiab] OR "GH administration"[tiab] OR "growth hormone injection"[tiab] OR "growth hormone injections"[tiab] OR "growth hormone supplementation"[tiab]) AND (testosteron*[tiab] OR hypogonad*[tiab] OR "androgen deficiency"[tiab]); human records 352; animal records 50. Formula: records returned by the stored query: humans NOT animals filter = humanRecords; animals NOT humans filter = animalRecords
Other peptides people research for testosterone
All peptides for testosterone, comparedCommon questions
Does HGH help with testosterone?
The strongest study we summarise for testosterone is human rct evidence, across 2 studies with an outcome for testosterone. A trial result is not an approval; see the legal status.
Is HGH approved for testosterone?
HGH is FDA approved (prescription only). Which conditions that approval covers is set by the label; use for anything else is off-label.
What is the best peptide for testosterone?
There is no single answer. Our testosterone overview compares each candidate by evidence grade and legal status rather than by popularity.
Does HGH increase testosterone?
The cited trials give testosterone separately; they do not report GH alone raising testosterone.[1]
More on HGH
Sources
- 1The effects of growth hormone and/or testosterone in healthy elderly men: a randomized controlled trial.The Journal of clinical endocrinology and metabolism · 2006PMID 16332938Accessed 2 Oct 2026
- 2Effects of growth hormone and/or sex steroid administration on whole-body protein turnover in healthy aged women and men.Metabolism: clinical and experimental · 2005PMID 16125527Accessed 2 Oct 2026
- 3Official web pageOfficial web page · web page
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