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Is retatrutide a steroid?

No: retatrutide (LY3437943) is described as a single peptide with agonist activity at the glucagon, GIP and GLP-1 receptors, not as a steroid.

GLP-1 / GIP / glucagon triple agonistUpdated

Short answer

No: retatrutide (LY3437943) is described as a single peptide with agonist activity at the glucagon, GIP and GLP-1 receptors, not as a steroid.[1]

What it is instead

A review calls it a first-in-class, unimolecular triple hormone receptor agonist at the GIP, GLP-1 and glucagon receptors.[2]

A review of unregulated injectables names the veterinary anabolic steroid trenbolone and the investigational triple agonist retatrutide as separate items in the same list.[3]

More questions on Retatrutide

Can retatrutide cause cancer?Can retatrutide cause high blood pressure?Can retatrutide cause joint pain?Can retatrutide cause pancreatitis?Can women take retatrutide?Can you build muscle on retatrutide?

More on Retatrutide

How it worksTarget, mechanism and how long it acts, from the label or studies.Retatrutide overview

Sources

  1. 1LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial.Lancet (London, England) · 2022PMID 36354040Accessed 2 Oct 2026
  2. 2Triple Hormone Receptor Agonism: The Role of Retatrutide in Addressing Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Comprehensive Review.Cardiology in review · 2026PMID 42108533Accessed 2 Oct 2026
  3. 3Dangers of Injectable Peptides and Other Unregulated "Biohacking" Drugs.Missouri medicine · 2026PMID 42757290Accessed 2 Oct 2026

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