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Can women take tesamorelin?

The label contraindicates tesamorelin in pregnant women.

GHRH analogUpdated

Short answer

The label contraindicates tesamorelin in pregnant women.[1]

What is known for women

The 412-person pivotal trial was 86% men, so it says little about women.[2]

The muscle analysis of two trials was also mostly male (87%), again limiting what can be said for women.[3]

In pregnancy, rats given tesamorelin during organogenesis had offspring with hydrocephaly, and the label says to stop the drug if pregnancy occurs (animal data).[1]

For breastfeeding, the label says mothers should not breastfeed while receiving the drug, citing HIV transmission, viral resistance and unknown drug effects.[1]

More questions on Tesamorelin

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More on Tesamorelin

Tesamorelin overview

Sources

  1. 1EGRIFTA SV prescribing information (FDA label)FDA label, DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026
  2. 2Metabolic effects of a growth hormone-releasing factor in patients with HIV.The New England journal of medicine · 2007PMID 18057338Accessed 2 Oct 2026
  3. 3The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV.The Journal of frailty & aging · 2019PMID 31237318Accessed 2 Oct 2026

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