Tesamorelin
GHRH analog. Tesamorelin is FDA approved (Egrifta); research-chemical versions are not the approved drug.
Key facts
How we verify- Class
- GHRH analog
- Also called
- tesa, Egrifta
- Vial sizes sold
- 2 mg, 5 mg, 10 mg, 20 mg
- Community-reported sizes
- Half-life
- 11 minutes
- subcutaneous (EGRIFTA WR 1.28 mg), in people · FDA label (Egrifta WR)
- FDA status
- Approved (Egrifta)
- Approved
- WADA
- Prohibited (S2.2.4)
- In and out of competition
Tesamorelin guides
Evidence at a glance
Human and animal counts are PubMed records from our evidence ledger (search counts, not studies we reviewed). The grade is the strongest design among the studies we summarised for that goal: a human randomized trial outweighs any number of animal studies.
| Condition | Human studies | Animal studies | Studies we summarised | Evidence grade |
|---|---|---|---|---|
| Weight loss | 34 | 0 | 10 | Human RCT evidence, 4 of 4eNeurologicalSci 2026, PMID 42382101 |
| Muscle growth | Not in our ledger | Not in our ledger | 0 | No graded study for this goal |
| Sleep | 1 | 0 | 1 | Human RCT evidence, 4 of 4eNeurologicalSci 2026, PMID 42382101 |
| Heart health | 13 | 0 | 6 | Human RCT evidence, 4 of 4Clinical infectious diseases 2012, PMID 22495074 |
| Diabetes | Not in our ledger | Not in our ledger | 0 | No graded study for this goal |
Grades follow our evidence scale. Summarised studies come from our evidence file, each quote checked against the abstract or label.
Compared with
Common stacks
Tesamorelin is often sold pre-mixed or combined with other peptides. No controlled study has tested these combinations; the pages below cover the math and what each part has been studied for.
Common questions
Is Tesamorelin FDA approved?
Tesamorelin is FDA approved (Egrifta). Products sold as research chemicals are not the approved drug and are not checked by the FDA.
Is Tesamorelin banned in sport?
Yes. Prohibited by WADA (S2.2.4), so it is prohibited at all times for tested athletes.
How much water goes in a 10 mg vial?
That choice only changes the concentration. With 2 mL, the vial is 5 mg/mL. The calculator converts any amount to syringe units. It does the math only and does not suggest a dose.
Sources
- 1US search volume and year-over-year trend, Google Keyword Planner export (Jun–Aug 2026 vs 2025)Peptigraph research · 2026peptigraph.com/methodology/Accessed 1 Oct 2026
- 2World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
- 3United States: Approved by FDA as Egrifta (original approval 10 Nov 2010), Theratechnologies, for reduction of excess abdominal fat in HIV-infected adults with lipodystrophy (label quote).U.S. Food and Drug Administration · 2026api.fda.govAccessed 2 Oct 2026
- 4FDA warning letters to five research-peptide sellersFDA warning letter (NuScience Peptides; 1 of 5) · 2026fda.govAccessed 2 Oct 2026
- 5The effect of growth hormone-releasing hormone on cognition and brain connectivity in adults with cognition ranging from normal to mild cognitive impairment.eNeurologicalSci · 2026PMID 42382101Accessed 2 Oct 2026
- 6Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012PMID 22495074Accessed 2 Oct 2026
- 7EGRIFTA WR (TESAMORELIN) KIT [THERATECHNOLOGIES INC.]FDA label (Egrifta WR), DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026
- 8PubMed search: (tesamorelin[tiab] OR Egrifta[tiab] OR TH9507[tiab] OR "TH-9507"[tiab]) (104 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 9PubMed search: (tesamorelin[tiab] OR TH9507[tiab]) AND (pharmacokinetic*[tiab] OR half-life[tiab]) (5 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
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