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Is tesamorelin a steroid?

The label describes tesamorelin as a synthetic analogue of human growth hormone-releasing factor made of 44 amino acids, a peptide rather than a steroid.

GHRH analogUpdated

Short answer

The label describes tesamorelin as a synthetic analogue of human growth hormone-releasing factor made of 44 amino acids, a peptide rather than a steroid.[1]

How it acts compared with a hormone drug

It binds the same receptors as the body's own releasing factor, so it prompts growth hormone release instead of supplying a hormone directly.[1]

In trials it raised growth hormone and IGF-1 without clinically significant changes in other pituitary hormones such as LH, TSH, ACTH and prolactin.[1]

In rats and dogs given the compound repeatedly, researchers saw a more pronounced anabolic effect in dogs and tied it to prolonged high growth hormone and IGF-1 exposure (animal data).[2]

More questions on Tesamorelin

Can tesamorelin cause weight gain?Can women take tesamorelin?Does tesamorelin cause cancer?Does tesamorelin cause water retention?Does tesamorelin help build muscle?Does tesamorelin show up on a drug test?

More on Tesamorelin

How it worksTarget, mechanism and how long it acts, from the label or studies.Tesamorelin overview

Sources

  1. 1EGRIFTA SV prescribing information (FDA label)FDA label, DailyMed · current labeldailymed.nlm.nih.govAccessed 2 Oct 2026
  2. 2Non-clinical pharmacology and safety evaluation of TH9507, a human growth hormone-releasing factor analogue.Basic & clinical pharmacology & toxicology · 2007PMID 17214611Accessed 11 Oct 2026

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