Survodutide
GLP-1 / glucagon dual agonist. Survodutide is investigational and not approved for any use.
Medically reviewed by Juan Pablo Frías, MD · · DisclosureUpdated Strongest evidence: Human RCT evidence, 4 of 4
Key facts
How we verify- Class
- GLP-1 / glucagon dual agonist
- Also called
- No common aliases
- Half-life
- Not found
- No published half-life found (PubMed search, 2 Oct 2026)
- FDA status
- Not approved
- Investigational · phase 3
- WADA
- Prohibited (S0)
- In and out of competition
Everything on Survodutide
Survodutide guides
Evidence at a glance
Human and animal counts are PubMed records from our evidence ledger (search counts, not studies we reviewed). The grade is the strongest design among the studies we summarised for that goal: a human randomized trial outweighs any number of animal studies.
| Condition | Human studies | Animal studies | Studies we summarised | Evidence grade |
|---|---|---|---|---|
| Any condition (no goal ledger yet) | Not in our ledger | Not in our ledger | 9 | Human RCT evidence, 4 of 4The New England journal of medicine 2026, PMID 42253238 |
Grades follow our evidence scale. Summarised studies come from our evidence file, each quote checked against the abstract or label.
Common questions
Is Survodutide FDA approved?
No. Survodutide is investigational (investigational · phase 3) and not approved for any use.
Is Survodutide banned in sport?
Yes. Prohibited by WADA (S0), so it is prohibited at all times for tested athletes.
Sources
- 1US search volume and year-over-year trend, Google Keyword Planner export (Jun–Aug 2026 vs 2025)Peptigraph research · 2026peptigraph.com/methodology/Accessed 1 Oct 2026
- 2World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
- 3United States: No FDA-approved product found: Drugs@FDA (openFDA) search for active ingredient "survodutide" returned no matches on 2 Oct 2026.U.S. Food and Drug Administration · 2026api.fda.govAccessed 2 Oct 2026
- 4FDA warning letters to five research-peptide sellersFDA warning letter (NuScience Peptides; 1 of 5) · 2026fda.govAccessed 2 Oct 2026
- 5Survodutide Once Weekly for the Treatment of Adults with Obesity.The New England journal of medicine · 2026PMID 42253238Accessed 2 Oct 2026
- 6PubMed search: survodutide[tiab] OR BI456906[tiab] (86 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 7PubMed search: (survodutide[tiab] OR BI456906[tiab]) AND (randomized[tiab] OR trial[tiab] OR phase[tiab]) (56 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 8PubMed search: (survodutide[tiab] OR BI456906[tiab]) AND (half-life[tiab] OR pharmacokinetic*[tiab]) (3 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
- 9PubMed search: (SYNCHRONIZE[tiab] OR TRIUMPH[tiab] OR GLORY[tiab] OR DREAMS[tiab]) AND (survodutide[tiab] OR retatrutide[tiab] OR mazdutide[tiab]) (27 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
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