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Is sermorelin a GLP-1?

No. The literature describes sermorelin as a 29-amino-acid analogue of growth hormone-releasing hormone, which is a different hormone from the incretins used for weight loss.

GHRH analogUpdated

Short answer

No. The literature describes sermorelin as a 29-amino-acid analogue of growth hormone-releasing hormone, which is a different hormone from the incretins used for weight loss.[1]

Its described effect is on the pituitary gland, where it stimulates growth hormone secretion; this abstract describes no incretin action.[1]

A recent review files sermorelin under growth hormone-releasing hormone analogues, in a list that also names tesamorelin and CJC-1295.[2]

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More on Sermorelin

Sermorelin overview

Sources

  1. 1Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 1999PMID 18031173Accessed 2 Oct 2026
  2. 2The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.Frontiers in endocrinology · 2026PMID 42395176Accessed 2 Oct 2026

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