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Is sermorelin a peptide?

Yes. A clinical drug review calls sermorelin the shortest synthetic peptide that keeps the full biological activity of GHRH.

GHRH analogUpdated

Short answer

Yes. A clinical drug review calls sermorelin the shortest synthetic peptide that keeps the full biological activity of GHRH.[1]

Older papers use the name GHRH-(1-29) for the same sequence, so searches for the peptide may need that label.[2]

What it does: it prompts the pituitary to secrete growth hormone, and in a diagnostic role a single intravenous dose is used as a test for growth hormone deficiency.[1]

The US maker of the branded product, Geref, announced it was discontinuing it in July 2008.[3]

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More on Sermorelin

Sermorelin overview

Sources

  1. 1Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 1999PMID 18031173Accessed 2 Oct 2026
  2. 2Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men.The Journal of clinical endocrinology and metabolism · 1992PMID 1379256Accessed 2 Oct 2026
  3. 3Clinical review: Is lack of recombinant growth hormone (GH)-releasing hormone in the United States a setback or time to consider glucagon testing for adult GH deficiency?The Journal of clinical endocrinology and metabolism · 2009PMID 19509104Accessed 2 Oct 2026

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