BPC-157 Dosage: Doses Studied, Units and Chart
What doses of BPC-157 have been used in published research, how they convert to syringe units, and what is still unknown.
- Doses studied
- 15 studies
- with a stated dose, listed below
- Frequency
- Varies by study
- as used in studies
- Half-life
- less than 30 min
- IV and IM (single and repeated), rat, beagle dog · Frontiers in pharmacology 2022, PMID 36588717
- Vial sizes sold
- 2 mg, 5 mg, 10 mg, 20 mg
Doses used in published studies
Each dose below is quoted from a study abstract, strongest design first. Animal doses are labelled and do not translate directly to people. None of them is a recommendation.
| Dose | Frequency and route | Study type | Source |
|---|---|---|---|
| 10 mg (day 1) and 20 mg (day 2) in 250 cc normal saline | once daily on 2 consecutive days · intravenous infusion over one hour · 2 days | Human uncontrolled trialn = 2 | Alternative therapies in health and medicine 2025, PMID 40131143 |
| 10 mg total | single procedure · injection around the inflamed bladder area during cystoscopy | Human uncontrolled trialn = 12 | Alternative therapies in health and medicine 2024, PMID 39325560 |
| BPC-157 10 ug/kg/day; TB-500 60 ug/kg/day | daily · intraperitoneal · four weeks | Animal · rat (not a human result)n = 32 | Joint diseases and related surgery 2026, PMID 42542926 |
| 10, 20 or 40 ug/kg | Not stated in the abstract | Animal · rat (not a human result) | Journal of dental anesthesia and pain medicine 2022, PMID 35449779 |
| 10 ng/kg, 10 ug/kg | intraperitoneal | Animal · rat (not a human result) | Biomedicines 2022, PMID 35203478 |
| 0.4 ug/eye, 0.4 ng/eye; 10 ug/kg, 10 ng/kg | eye drops, intraperitoneal or drinking water · six weeks | Animal · rat (not a human result) | Biomedicines 2021, PMID 35052769 |
| 200 or 2 ug/kg | single injection 10 min after injury · intraperitoneal | Animal · rat (not a human result) | Journal of orthopaedic surgery and research 2019, PMID 31266512 |
| 10 ug/kg | bath applied to the colon segment | Animal · rat (not a human result) | World journal of gastroenterology 2017, PMID 29358856 |
| 10 ug/kg or 10 ng/kg | once daily · intraperitoneal or in drinking water | Animal · rat (not a human result) | Journal of physiology and pharmacology 2013, PMID 24304574 |
| 10 microg or 10 ng/kg i.p.; 1.0 microg/g cream topically; 0.16 microg/ml in drinking water | once daily · intraperitoneal, topical cream or oral (drinking water) | Animal · rat (not a human result) | Journal of orthopaedic research 2010, PMID 20225319 |
| 10 microg, 10 ng/kg | intraperitoneal, intragastric or local | Animal · rat (not a human result) | Regulatory peptides 2010, PMID 19903499 |
| 10 microg/kg, 10 ng/kg | continuously in drinking water, or once daily i.p. · drinking water or intraperitoneal | Animal · rat (not a human result) | Journal of pharmacological sciences 2008, PMID 18818478 |
| 1 microg, 1 ng or 1 pg per g of neutral cream | once daily · topical cream | Animal · mouse (not a human result) | Burns 2005, PMID 15774286 |
| 10 microg, 10 ng or 10 pg/kg | once daily, first dose 30 min after surgery · intraperitoneal | Animal · rat (not a human result) | Journal of orthopaedic research 2003, PMID 14554208 |
| 10 microg or 10 ng/kg | once daily (postoperative days 7-21) or intermittent doses on postoperative days 7, 9, 14 and 16 · local percutaneous or intramuscular · postoperative days 7-21 for the daily regimen | Animal · rabbit (not a human result) | Bone 1999, PMID 10071911 |
Dose to syringe units
For a 10 mg vial mixed with 2 mL of bacteriostatic water (5 mg/mL), on a U-100 syringe. These are reference amounts for the math, not suggested doses.
- 100 mcg
- 2 u
- 200 mcg
- 4 u
- 250 mcg
- 5 u
- 300 mcg
- 6 u
- 400 mcg
- 8 u
- 500 mcg
- 10 u
Before anyone considers it
- BPC-157 is not FDA approved for any use.
- Products sold as research chemicals are not checked by the FDA for identity, purity or dose.
- Reconstitution math (mg vs mcg, units vs mL) is the most asked question in peptide forums. Check every number twice.
- People who are pregnant, breastfeeding, or have a chronic condition need medical advice first.
Common questions
How many units is 250 mcg of BPC-157?
It depends on the water added. A 10 mg vial with 2 mL of water gives 5 mg/mL, so 250 mcg is 5 units on a U-100 syringe. Use the calculator for other mixes.
Is BPC-157 FDA approved?
No. BPC-157 is not FDA approved for any use. The FDA removed it from Category 2 on 15 Apr 2026. Its advisory committee voted 8–6 in July 2026 to add it to the 503A compounding list. That vote is not final.
More on BPC-157
Side effectsWhat labels and studies report, and what is unknown.CalculatorVial, water and dose to syringe units.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.Legal statusFDA, compounding and WADA status with dates.How to injectSites, syringe types and hygiene, step by step.
Sources
- 1Certain bulk drug substances for use in compounding that may present significant safety risks (Category 2; 'nominated but withdrawn' table, content current as of 22 Apr 2026)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
- 2Pharmacy Compounding Advisory Committee meeting, 23–24 Jul 2026 (agenda and materials)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
- 3Metric (SI) Prefixes (NIST Reference on Constants, Units, and Uncertainty)National Institute of Standards and Technology (NIST) · 2025physics.nist.govAccessed 2 Oct 2026
- 4BASAGLAR (insulin glargine) injection, prescribing information (DailyMed)U.S. Food and Drug Administration / DailyMed (Eli Lilly and Company label) · 2026dailymed.nlm.nih.govAccessed 2 Oct 2026
- 5Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study.Alternative therapies in health and medicine · 2025PMID 40131143Accessed 2 Oct 2026
- 6Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study.Alternative therapies in health and medicine · 2024PMID 39325560Accessed 2 Oct 2026
- 7Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study.Joint diseases and related surgery · 2026PMID 42542926Accessed 2 Oct 2026
- 8The anti-nociceptive effect of BPC-157 on the incisional pain model in rats.Journal of dental anesthesia and pain medicine · 2022PMID 35449779Accessed 2 Oct 2026
- 9Stable Gastric Pentadecapeptide BPC 157 May Counteract Myocardial Infarction Induced by Isoprenaline in Rats.Biomedicines · 2022PMID 35203478Accessed 2 Oct 2026
- 10Stable Gastric Pentadecapeptide BPC 157 Therapy of Rat Glaucoma.Biomedicines · 2021PMID 35052769Accessed 2 Oct 2026
- 11Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats.Journal of orthopaedic surgery and research · 2019PMID 31266512Accessed 2 Oct 2026
- 12Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights.World journal of gastroenterology · 2017PMID 29358856Accessed 2 Oct 2026
- 13Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society · 2013PMID 24304574Accessed 2 Oct 2026
- 14Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2010PMID 20225319Accessed 2 Oct 2026
- 15Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury.Regulatory peptides · 2010PMID 19903499Accessed 2 Oct 2026
- 16Pentadecapeptide BPC 157, in clinical trials as a therapy for inflammatory bowel disease (PL14736), is effective in the healing of colocutaneous fistulas in rats: role of the nitric oxide-system.Journal of pharmacological sciences · 2008PMID 18818478Accessed 2 Oct 2026
- 17The stable gastric pentadecapeptide BPC 157, given locally, improves CO2 laser healing in mice.Burns : journal of the International Society for Burn Injuries · 2005PMID 15774286Accessed 2 Oct 2026
- 18Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2003PMID 14554208Accessed 2 Oct 2026
- 19Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits: a comparison with bone marrow and autologous cortical bone implantation.Bone · 1999PMID 10071911Accessed 2 Oct 2026
- 20Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs.Frontiers in pharmacology · 2022PMID 36588717Accessed 2 Oct 2026
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