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BPC-157

Gastric pentadecapeptide. BPC-157 is not FDA approved for any use.

Also called:BPCbody protection compoundPentadecapeptide BPC 157
Medically reviewed by Juan Pablo Frías, MD · · DisclosureUpdated Strongest evidence: Human observational evidence, 3 of 4
StatusPCAC voted 8–6 for 503A (Jul 2026)Removed from FDA Category 2 on 15 Apr 2026. PCAC voted 8–6 for the 503A list (Jul 2026); not finalized.Prohibited by WADA (S0)Full legal history

Key facts

How we verify
Class
Gastric pentadecapeptide
Also called
BPC, body protection compound
Vial sizes sold
2 mg, 5 mg, 10 mg, 20 mg
Community-reported sizes
Half-life
less than 30 min
IV and IM (single and repeated), rat, beagle dog · Frontiers in pharmacology 2022, PMID 36588717
FDA status
Not approved
Off Category 2, 15 Apr 2026
PCAC vote
8–6 for 503A
Jul 2026, not final
WADA
Prohibited (S0)
In and out of competition
Everything on BPC-157

BPC-157 guides

DosageDoses used in published studies, with the source for each.Side effectsWhat labels and studies report, and what is unknown.CalculatorVial, water and dose to syringe units.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.Legal statusFDA, compounding and WADA status with dates.How to injectSites, syringe types and hygiene, step by step.Half-lifeWhat is measured, by route, and what is not.StoragePowder and mixed vials: temperature and shelf life.10 mg vialConcentration and unit tables for the 10 mg size.For injury recoveryWhat research says about BPC-157 for injury recovery.For inflammationWhat research says about BPC-157 for inflammation.For gut healthWhat research says about BPC-157 for gut health.
Vial and dose sizes
5 mg vial20 mg vial
Researched for
weight lossheart healthfibromyalgiajoint painskinliver health

Evidence at a glance

Human and animal counts are PubMed records from our evidence ledger (search counts, not studies we reviewed). The grade is the strongest design among the studies we summarised for that goal: a human randomized trial outweighs any number of animal studies.

BPC-157: studies by condition
ConditionHuman studiesAnimal studiesStudies we summarisedEvidence grade
Injury recovery74614Animal evidence, 2 of 4Joint diseases and related surgery 2026, PMID 42542926
Inflammation8432Animal evidence, 2 of 4Journal of physiology and pharmacology 2013, PMID 24304574
Gut health5874Animal evidence, 2 of 4World journal of gastroenterology 2017, PMID 29358856
Weight lossNot in our ledgerNot in our ledger0No graded study for this goal
Heart health351Animal evidence, 2 of 4Biomedicines 2022, PMID 35203478
Fibromyalgia000No graded study for this goal
Joint pain302Human observational evidence, 3 of 4Alternative therapies in health and medicine 2021, PMID 34324435
Skin042Animal evidence, 2 of 4Burns 2005, PMID 15774286
Liver health3221Animal evidence, 2 of 4Life sciences 2022, PMID 36228773

Grades follow our evidence scale. Summarised studies come from our evidence file, each quote checked against the abstract or label.

Compared with

BPC-157vsTB-500Gastric pentadecapeptide next to synthetic fragment of thymosin beta-4: evidence, dosing and legal status side by side.PCAC voted 8–6 for 503A (Jul 2026)Read the comparison →BPC-157vsSermorelinGastric pentadecapeptide next to ghrh analog: evidence, dosing and legal status side by side.Compounded by prescriptionRead the comparison →BPC-157vsKPVGastric pentadecapeptide next to anti-inflammatory tripeptide: evidence, dosing and legal status side by side.PCAC voted 8–6 for 503A (Jul 2026)Read the comparison →BPC-157vsCJC-1295Gastric pentadecapeptide next to ghrh analog: evidence, dosing and legal status side by side.Not FDA approved · research chemicalRead the comparison →

Common stacks

BPC-157 is often sold pre-mixed or combined with other peptides. A few of these pairs appear together in published studies; each stack page lists what was tested, and the pages below cover the math and what each part has been studied for.

KLOWGHK-Cu, BPC-157, TB-500 and KPV80 mg blendsBlend calculator
GLOWGHK-Cu, BPC-157 and TB-50050 mg · 70 mg blendsBlend calculator
WolverineBPC-157 and TB-50010 mg · 20 mg blendsBlend calculator
BPC-157 + KPVBPC-157 + WolverineBPC-157 + SermorelinBPC-157 + CJC-1295

Common questions

Is BPC-157 FDA approved?

No. BPC-157 is not FDA approved for any use. The FDA removed it from Category 2 on 15 Apr 2026. Its advisory committee voted 8–6 in July 2026 to add it to the 503A compounding list. That vote is not final.

Is BPC-157 banned in sport?

Yes. Prohibited by WADA (S0), so it is prohibited at all times for tested athletes.

How much water goes in a 10 mg vial?

That choice only changes the concentration. With 2 mL, the vial is 5 mg/mL. The calculator converts any amount to syringe units. It does the math only and does not suggest a dose.

Sources

  1. 1Certain bulk drug substances for use in compounding that may present significant safety risks (Category 2; 'nominated but withdrawn' table, content current as of 22 Apr 2026)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  2. 2Pharmacy Compounding Advisory Committee meeting, 23–24 Jul 2026 (agenda and materials)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  3. 3US search volume and year-over-year trend, Google Keyword Planner export (Jun–Aug 2026 vs 2025)Peptigraph research · 2026peptigraph.com/methodology/Accessed 1 Oct 2026
  4. 4World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
  5. 5United States: No FDA-approved product found: Drugs@FDA (openFDA) search for active ingredient "BPC-157" returned no matches on 2 Oct 2026.U.S. Food and Drug Administration · 2026api.fda.govAccessed 2 Oct 2026
  6. 6US compounding: BPC-157 was removed from FDA's 503A category 2 because the nominators withdrew; FDA announced a Pharmacy Compounding Advisory Committee consultation on 23 July 2026 on whether to add it to the 503A bulks list.U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  7. 7World Anti-Doping Code: Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
  8. 8Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study.Joint diseases and related surgery · 2026PMID 42542926Accessed 2 Oct 2026
  9. 9Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society · 2013PMID 24304574Accessed 2 Oct 2026
  10. 10Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights.World journal of gastroenterology · 2017PMID 29358856Accessed 2 Oct 2026
  11. 11Stable Gastric Pentadecapeptide BPC 157 May Counteract Myocardial Infarction Induced by Isoprenaline in Rats.Biomedicines · 2022PMID 35203478Accessed 2 Oct 2026
  12. 12Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.Alternative therapies in health and medicine · 2021PMID 34324435Accessed 2 Oct 2026
  13. 13The stable gastric pentadecapeptide BPC 157, given locally, improves CO2 laser healing in mice.Burns : journal of the International Society for Burn Injuries · 2005PMID 15774286Accessed 2 Oct 2026
  14. 14Pentadecapeptide BPC 157 efficiently reduces radiation-induced liver injury and lipid accumulation through Kruppel-like factor 4 upregulation both in vivo and in vitro.Life sciences · 2022PMID 36228773Accessed 2 Oct 2026
  15. 15Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study.Alternative therapies in health and medicine · 2025PMID 40131143Accessed 2 Oct 2026
  16. 16Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs.Frontiers in pharmacology · 2022PMID 36588717Accessed 2 Oct 2026
  17. 17PubMed search: "BPC-157"[tiab] OR BPC157[tiab] OR "body protection compound"[tiab] OR "pentadecapeptide BPC"[tiab] (230 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  18. 18PubMed search: ("BPC-157"[tiab] OR BPC157[tiab] OR "body protection compound"[tiab]) AND (half-life[tiab] OR pharmacokinetic*[tiab]) (7 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  19. 19PubMed search: "BPC-157"[tiab] AND humans[mh] (52 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  20. 20PubMed search: ("BPC-157"[tiab] OR BPC157[tiab] OR "body protection compound"[tiab] OR "pentadecapeptide BPC"[tiab]) AND (patients[tiab] OR clinical trial[pt] OR randomized[tiab]) (25 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  21. 21PubMed search: ("BPC-157"[tiab] OR BPC157[tiab] OR "body protection compound"[tiab] OR "pentadecapeptide BPC"[tiab]) AND (colitis[tiab] OR inflammatory bowel[tiab]) (48 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  22. 22PubMed search: ("BPC-157"[tiab] OR BPC157[tiab] OR "body protection compound"[tiab] OR "pentadecapeptide BPC"[tiab]) AND (tendon[tiab] OR ligament[tiab] OR muscle[tiab] OR bone[tiab] OR arthritis[tiab]) (58 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  23. 23PubMed search: ("BPC-157"[tiab] OR BPC157[tiab] OR "body protection compound"[tiab] OR "pentadecapeptide BPC"[tiab]) AND (nerve[tiab] OR neuropath*[tiab] OR spinal[tiab] OR liver[tiab] OR wound[tiab] OR burn[tiab]) (90 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  24. 24Advisory committee backs 6 of 7 peptides for the 503A listNCPA · 2026ncpa.org
  25. 25FDA gives notice that 12 peptides will be removed from Category 2 (nominations withdrawn)FDA · 2026fda.govAccessed 2 Oct 2026

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