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BPC-157 Half-Life: How Long It Stays in Your System

How long BPC-157 stays in the body, how that shapes dosing frequency, and what is known about drug testing.

Medically reviewed by Juan Pablo Frías, MD · · DisclosureGastric pentadecapeptideUpdated
Half-life
less than 30 min
IV and IM (single and repeated), rat, beagle dog · Frontiers in pharmacology 2022, PMID 36588717
Dosing interval
Varies by study
as used in studies
WADA
Prohibited (S0)
In and out of competition
Detection window
2 findings
from anti-doping studies, below

BPC-157 half-life

A half-life depends on the route (under the skin, into a vein, by mouth or nasal spray) and the species it was measured in, so we report each value with its route and source.

BPC-157 half-life by route
RouteHalf-lifeMeasured inSource
IV and IM (single and repeated)less than 30 minAnimal · rat, beagle dogFrontiers in pharmacology 2022, PMID 36588717
not stated (review summary)less than 30 minutesAnimal · review of preclinical dataHSS journal 2025, PMID 40756949

What half-life means

Half-life is the time it takes for the amount of a drug in the blood to fall by half. After one half-life, about 50% is left; after two, about 25%; after four to five, only a few percent remain.

  • A long half-life lets a drug be dosed less often, for example once a week.
  • A short half-life means levels rise and fall quickly, which is why some peptides are given daily or more often.
  • Effects can outlast blood levels, so half-life alone does not tell you how long a drug works.

What it means for dosing frequency

Dosing intervals used in published studies of BPC-157:

Changing the interval changes how much drug builds up between doses, so it is not a free choice.

Drug tests and sport

Prohibited by WADA (S0)

BPC-157 is named in S0 (non-approved substances), prohibited at all times, in and out of competition.

Detection findings from anti-doping analytical studies:

  • A 2023 method detects BPC-157 and five main metabolites in human urine at very low concentrations. · PMID 37959764
  • A 2017 anti-doping lab method detects BPC 157 in urine; the peptide was stable in urine for at least 4 days. · PMID 28035768

Tested athletes should treat it as prohibited (s0) at all times.

Common questions

How long does BPC-157 stay in your system?

Its reported half-life is less than 30 min (IV and IM (single and repeated), rat, beagle dog); less than 30 minutes (not stated (review summary), review of preclinical data). Most of a dose is gone after about four to five half-lives.

What is the half-life of BPC-157?

Less than 30 min (IV and IM (single and repeated), rat, beagle dog); less than 30 minutes (not stated (review summary), review of preclinical data), from the sources cited below.

Is BPC-157 on the WADA prohibited list?

Yes. Prohibited by WADA (S0).

More on BPC-157

DosageDoses used in published studies, with the source for each.CalculatorVial, water and dose to syringe units.Side effectsWhat labels and studies report, and what is unknown.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.Legal statusFDA, compounding and WADA status with dates.

Sources

  1. 1Certain bulk drug substances for use in compounding that may present significant safety risks (Category 2; 'nominated but withdrawn' table, content current as of 22 Apr 2026)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  2. 2Pharmacy Compounding Advisory Committee meeting, 23–24 Jul 2026 (agenda and materials)U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  3. 3World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
  4. 4Stable Isotope Labeling-Based Nontargeted Strategy for Characterization of the In Vitro Metabolic Profile of a Novel Doping BPC-157 in Doping Control by UHPLC-HRMS.Molecules (Basel, Switzerland) · 2023PMID 37959764Accessed 2 Oct 2026
  5. 5Detection and in vitro metabolism of the confiscated peptides BPC 157 and MGF R23H.Drug testing and analysis · 2017PMID 28035768Accessed 2 Oct 2026
  6. 6Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs.Frontiers in pharmacology · 2022PMID 36588717Accessed 2 Oct 2026
  7. 7Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2025PMID 40756949Accessed 2 Oct 2026
  8. 8Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study.Alternative therapies in health and medicine · 2025PMID 40131143Accessed 2 Oct 2026
  9. 9Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study.Alternative therapies in health and medicine · 2024PMID 39325560Accessed 2 Oct 2026
  10. 10Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study.Joint diseases and related surgery · 2026PMID 42542926Accessed 2 Oct 2026
  11. 11Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats.Journal of orthopaedic surgery and research · 2019PMID 31266512Accessed 2 Oct 2026

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