How long has BPC-157 been studied?
About three decades: a systematic review found papers on it dated from 1993 through 2024.
Gastric pentadecapeptideUpdated
Short answer
About three decades: a systematic review found papers on it dated from 1993 through 2024.[1]
After screening, only 36 studies were included and just 1 was clinical, so the long timeline is mostly animal research.[1]
Early animal work and recent human reports
An early animal study tested it on segmental bone defects in rabbits.[2]
A small human pilot of intravenous infusion reported it was tolerated, with no side effects reported.[3]
More questions on BPC-157
More on BPC-157
Sources
- 1Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2025PMID 40756949Accessed 2 Oct 2026
- 2Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits: a comparison with bone marrow and autologous cortical bone implantation.Bone · 1999PMID 10071911Accessed 2 Oct 2026
- 3Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study.Alternative therapies in health and medicine · 2025PMID 40131143Accessed 2 Oct 2026
Found an error? Report a correction.