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Kisspeptin-10

GnRH stimulator. Kisspeptin-10 is Not FDA approved · research chemical; research-chemical versions are not the approved drug.

Also called:kiss
Medically reviewed by Juan Pablo Frías, MD · · DisclosureUpdated Strongest evidence: Human RCT evidence, 4 of 4
StatusNot FDA approved · research chemicalProhibited by WADA (S2.2.1)Full legal history

Key facts

How we verify
Class
GnRH stimulator
Also called
kiss
Vial sizes sold
5 mg, 10 mg
Community-reported sizes
Half-life
mean elimination half-life 1.3-2.2 hours
subcutaneous (analog MVT-602), in people · Fertility and sterility 2024, PMID 37925096
FDA status
Not FDA approved · research chemical
No approved product found
WADA
Prohibited (S2.2.1)
In and out of competition
Everything on Kisspeptin-10

Kisspeptin-10 guides

DosageDoses used in published studies, with the source for each.Side effectsWhat labels and studies report, and what is unknown.CalculatorVial, water and dose to syringe units.ResultsStudy outcomes and when they were measured.PricePrice per mg and per week from dated listings. No vendor links.For testosteroneWhat research says about Kisspeptin-10 for testosterone.For menopauseWhat research says about Kisspeptin-10 for menopause.For liver healthWhat research says about Kisspeptin-10 for liver health.

Evidence at a glance

Human and animal counts are PubMed records from our evidence ledger (search counts, not studies we reviewed). The grade is the strongest design among the studies we summarised for that goal: a human randomized trial outweighs any number of animal studies.

Kisspeptin-10: studies by condition
ConditionHuman studiesAnimal studiesStudies we summarisedEvidence grade
Testosterone8313Human RCT evidence, 4 of 4European journal of endocrinology 2026, PMID 42549827
Menopause310No graded study for this goal
Liver health033Animal evidence, 2 of 4Cells 2025, PMID 40862768

Grades follow our evidence scale. Summarised studies come from our evidence file, each quote checked against the abstract or label.

Compared with

Kisspeptin-10vsPT-141GnRH stimulator next to melanocortin agonist: evidence, dosing and legal status side by side.FDA approved for HSDD (Vyleesi)Read the comparison →Kisspeptin-10vsEnclomipheneGnRH stimulator next to serm (not a peptide): evidence, dosing and legal status side by side.Not FDA approved · compoundedRead the comparison →

Common stacks

Kisspeptin-10 is often sold pre-mixed or combined with other peptides. A few of these pairs appear together in published studies; each stack page lists what was tested, and the pages below cover the math and what each part has been studied for.

Kisspeptin-10 + hCGKisspeptin-10 + PT-141

Common questions

Is Kisspeptin-10 FDA approved?

Kisspeptin-10 is Not FDA approved · research chemical. Products sold as research chemicals are not the approved drug and are not checked by the FDA.

Is Kisspeptin-10 banned in sport?

Yes. Prohibited by WADA (S2.2.1), so it is prohibited at all times for tested athletes.

How much water goes in a 10 mg vial?

That choice only changes the concentration. With 2 mL, the vial is 5 mg/mL. The calculator converts any amount to syringe units. It does the math only and does not suggest a dose.

Sources

  1. 1US search volume and year-over-year trend, Google Keyword Planner export (Jun–Aug 2026 vs 2025)Peptigraph research · 2026peptigraph.com/methodology/Accessed 1 Oct 2026
  2. 2World Anti-Doping Code International Standard Prohibited List 2026World Anti-Doping Agency · 2026wada-ama.orgAccessed 2 Oct 2026
  3. 3United States: No FDA-approved product found: Drugs@FDA (openFDA) search for active ingredient "Kisspeptin-10" returned no matches on 2 Oct 2026.U.S. Food and Drug Administration · 2026api.fda.govAccessed 2 Oct 2026
  4. 4US compounding: Kisspeptin-10 is in FDA's 503A category 2 (significant safety risks), added 29 September 2023.U.S. Food and Drug Administration · 2026fda.govAccessed 2 Oct 2026
  5. 5Chronic subcutaneous kisspeptin-10 stimulates gonadotropin secretion for 12 days in healthy men.European journal of endocrinology · 2026PMID 42549827Accessed 2 Oct 2026
  6. 6Kisspeptin Mitigates Hepatic De Novo Lipogenesis in Metabolic Dysfunction-Associated Steatotic Liver Disease.Cells · 2025PMID 40862768Accessed 2 Oct 2026
  7. 7Endocrine profile of the kisspeptin receptor agonist MVT-602 in healthy premenopausal women with and without ovarian stimulation: results from 2 randomized, placebo-controlled clinical tricals.Fertility and sterility · 2024PMID 37925096Accessed 2 Oct 2026
  8. 8PubMed search: ("kisspeptin-10"[tiab] OR "kisspeptin 10"[tiab]) AND humans[mh] (110 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  9. 9PubMed search: (kisspeptin[tiab]) AND humans[mh] AND (randomized controlled trial[pt] OR clinical trial[pt]) (54 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  10. 10PubMed search: kisspeptin[tiab] AND (half-life[tiab] OR pharmacokinetic*[tiab]) AND humans[mh] (13 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  11. 11PubMed search: kisspeptin[tiab] AND humans[mh] AND (men[tiab] OR male[tiab]) AND (testosterone[tiab] OR hypogonadism[tiab]) (90 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  12. 12PubMed search: kisspeptin[tiab] AND (menopaus*[tiab] OR postmenopaus*[tiab]) (89 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026
  13. 13PubMed search: kisspeptin[tiab] AND (liver[tiab] OR NAFLD[tiab] OR hepatic[tiab]) (68 results)PubMed · 2026pubmed.ncbi.nlm.nih.govAccessed 2 Oct 2026

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